If you’re a fan of Fox’s Lie to Me or generally have an interest in detecting deception, NPR’s Dina Temple-Raston did an interesting piece for Morning Edition entitled “Spotting Lies: Listen, Don’t Look.”
For more information on the science behind detecting deception through facial expressions, see Dr. Paul Ekman’s site. Dr. Ekman is the forefather of the study of microexpressions. His site includes microexpression training exercises and a column breaking down the real and embellished aspects of Lie to Me.